报告题目:Redirecting cellular trafficking: Instructions from a bacterium
报 告 人:罗招庆 博士(美国普渡大学)
报告时间:2013年4月3日(星期三)下午14:00-16:00
报告地点:成都校区图书馆报告厅
主办单位:农学院高端学术讲堂
动物医学院预防兽医研究所(教育部创新团队教授学术论坛)
报告人简介
罗招庆,博士,1991年中国农业大学植物病理专业本科毕业,1994年在该校获植物病理专业硕士学位,2001年毕业于国际知名的厄巴纳伊利诺斯州大学,获微生物学专业博士学位,而后在波斯顿塔夫斯大学医学院博士后流动站从事病原微生物学研究,2004年出站后一直在普渡大学从事科学研究。
曾先后以PI身份主持科研项目10余项,在国际学术会议发言交流10余次,在国内外科研院所作专题报告近30场。罗博士是PNAS、The EMBO Journal、Cellular Microbiology、Molecular Microbiology等近20种权威专业期刊审稿人,近十年在国际权威期刊发表研究论文30余篇。
近几年发表部分论文:
1.Banga S, Gao P, Shen X, Fiscus V, Zong WX, Chen L, Luo Z.-Q.Legionella pneumophila inhibits macrophage apoptosis by targeting pro-death members of the Bcl2 protein family. ProcNatlAcadSci USA 2007; 104:5121-6. PMID: 17360363
2.Liu Y., Gao P. Banga S. Luo Z.-Q.An In vivo gene deletion system for determining temporal requirement of bacterial virulence factors. 2008 ProcNatlAcadSci USA. 105:9385-90. PMID: 18599442
3.Shen X., Banga S., Liu Y., Xu L., Gao P., Shamovsky I., Nudler E. and Luo Z.-Q. 2009. Targeting eEF1A by a Legionella pneumophila effector leads to inhibition of protein synthesis and induction of host stress response. Cellular Microbiology.11: 911-926. PMID: 19386084
4.Xu L., Shen X., Bryan A., Banga S., Swanson M. and Luo Z.-Q. 2010. Inhibition of host vacuolar H+-ATPase activity by a Legionella pneumophila effector PLoS Pathogens19;6(3):e1000822. PMID: 20333253
5.Chen C.,BangaS., Mertens, K., WeberM., Gorbaslieva, I., Luo, Z.-Q*. and Samuel J. E. * 2010 Large-scale identification and translocation of type IV secretion substrates by CoxiellaburnetiiProcNatlAcadSci USA. 107:21755-21760. (†, Co-first authors; *, Co-corresponding authors). PMID: 21098666.
6.Fontana M. F., Banga S., Barry K. C., Shen X., Tan, Y., Luo Z.-Q*. and Vance E.V*. Secreted bacterial effectors that inhibit host protein synthesis are critical for induction of the innate immune response to virulent Legionella pneumophila. 2011. PLoS Pathogens.7: e1001289. (*, co-corresponding authors) PMID: 21390206
7.Luo Z.-Q. Striking a balance: Modulation of host cell death pathways by Legionella pneumophila. 2011. Front. Microbio.doi: 10.3389/fmicb.2011.00036 . PMID: 21687427
8. Zhu W., Banga S., Tan Y., Zheng C., Stephenson R., Gately J. and Luo Z.-Q. Comprehensive identification of protein substrates of the Dot/Icm type IV transporter of Legionella pneumophila. 2011. PLoS One .6(3):e17638. PMID: 21408005
9.Tan Y. and Luo Z.-Q.Legionella pneumophila SidD is a deAMPylase that modifies Rab1. 2011. Nature. 475:506-9. PMID: 21734656
10. Tan Y. and Luo Z.-Q.Take it and release it: The use of the Rab1 small GTPase at a bacterium's will.2011 Cell Logist.;1:125-127. PMID: 22279610
11.Jain P. Luo Z.-Q. and Blanke S.R.Helicobacter pylorivacuolatingcytotoxin A (VacA) engages the mitochondrial fission machinery to induce host cell death. 2011. ProcNatlAcadSci USA. 108:16032-7. PMID: 21903925
12.Tan Y., Arnold R. J., Luo Z.-Q.Legionella pneumophila regulates the small GTPase Rab1 activity by reversible phosphorylcholination. 2011. ProcNatlAcadSci USA.108:21212-7. PMID: 22158903.
13. Luo Z.-Q. Legionella secreted effectors and innate immune responses. Cellular Microbiology. 2012. Cell Microbiol.14:19-27. PMID:21985602
14.Hsu F, Zhu W., Brennan L., Tao L., Z.-Q. Luo and Mao Y. Structural basis for substrate recognition by a unique Legionellaphosphoinositide phosphatase. 2012. ProcNatlAcadSci USA 109:13567–72 PMID: 21985602
15. Xu L, Luo Z.-Q. Cell biology of infection by Legionella pneumophila. 2013. Microbes Infection.15:157-67. PMID: 23159466